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Our formula is third-party independently tested for heavy metals, impurities, made in the USA, GMP certified, and produced in an FDA registered facility. 1% of the supplements on the market can match our world-class standards.

●        Supports antioxidant function via decreased inflammatory cytokines (inflammation), decreased reactive oxygen species, and increased l-glutathione production (master antioxidant) (182,183).

●        Supports visual health via increased amounts of plasma vitamin A in macular (eye) tissues (182,1830.

●        Supports immune health via increased oxidant, free radical scavenging, and fueling neutrophilic (immune cell) activity in chemotaxis, phagocytosis, and microbial killing (97,98).

●        Supports fat burning by increasing carnitine biosynthesis (molecule required for mitochondrial fatty acid oxidation) (97,98).

●        Supports accelerate bone healing after a fracture, increase type I collagen synthesis, and reduce oxidative stress (inflammation) (98).

●        Supports hormonal health via high amounts of vitamin D receptor (VDR) activity in hormone-based negative feedback loop reactions (77,78).

●        Supports cardiovascular health via improved absorption of calcium, reduced atherosclerotic activity, stimulating cardiomyocytes, and improved vascular health (77,78).

●        Supports exercise performance via reduced exercise-associated inflammation and muscle damage (77,78).

●        Supports sexual health via increased activity of Vitamin D receptor activity of testosterone production (79).

●        Supports immune function via decreases of inflammatory cytokines and aiding immune cells (77,78).

●        Supports joint health via regulating calcium and phosphorus and bone remodeling along with other calcium-regulating actions (77,78).

●        Supports immune health via neutralizing free radicals and reactive oxygen species, and increased T lymphocyte-mediated immune function (204).

●        Supports cardiovascular health via reduced cholesterol (204).

●        Supports cognitive function via reduced oxidative stress, inflammation, and DNA damage of neuronal tissues (208).

●        Supports cardiovascular function and aids as a neuroprotective agent in individuals with vitamin B-1 deficiencies (94, 95).

●       Reduces conversion of VLDL into LDL proteins and serum lipoprotein concentrations in plasma (blood) (9).

●       Vital for regulation of gene expression, cell cycle progression, and DNA repair, and cell death (9).

●       Supports healthy inflammatory response via antioxidant and anti-apoptotic (prevention of cell death) properties (9).

●       Prevents pathologies(diseases) such as Pellagra and reduces prevalence of nervous anorexia, cancer, and crohn’s disease (10, 11).

●       Supports sensitization of tumors to radiation via apoptosis (cell death) cascade of tumor mass and improves oxygen delivery to malignant tissues (cancer cells) (12).

●       Supports cognitive health by reducing age-related decline of NAD+, increasing quinolinic acid and reducing neuroinflammation (9).

●       Increased niacin associated NAD+ levels have been shown to increase neurotransmission, learning and memory (9).

●       Niacin reduces the prevalence of neurodegenerative pathologies by preventing mitochondrial dysfunction (9).

●        Reduces plasma glucose (blood sugar levels) via by inhibiting the activity of small-intestinal α-glucosidases (enzymes associated with glucose metabolism) (39).

●        Functions as an antioxidant by counteracting the formation of reactive oxygen species (inflammatory markers) and advanced glycation end-products (38,40).

●        May support blood sugar regulation in women with gestational diabetes (40).

●        Cofactor for enzymes involved in DNA metabolism (40).

●       Enhances glucose breakdown into skeletal muscle tissue (213,214).

●       Regulates processes of bone resorption, mineralization, and fracture repair (36,37).

●        Increases the effect of physical exercise on bone mineral acquisition in the period preceding puberty (36,37).

●        Prevents the development of preeclampsia (36,37).

●        May increases oxygen uptake into red blood cells of Iron deficient individuals (215,216).

●        May support gut health of iron-deficient individuals.

●        Combats anemia in Iron deficient individuals (217).

●        Supports biological reactions such as ATP-fueled reactions and pancreatic insulin secretion (90,91).

●        Supports reduction systolic blood pressure, fasting glucose, triglycerides, and healthy HDL levels (90,91).

●        Reduces peripheral cortisol levels in the CNS and supports relaxation and decreased anxiety (90,91).

●         Supports stimulation of the innate and adaptive immune system (172,173).

●        Supports the activation of lymphocytes and activation of innate and T cell-mediated immunity (172,173).

●        Supports cognitive function by modulation of neuronal signaling in areas of the brain associated with memory and learning (hippocampus) (172,173).

●        Combats atherosclerosis, high cholesterol (hypercholesterolemia), and type 1 diabetes (147).

●        Supports thyroid health via decreased circulating thyroid autoantibodies in patients with chronic autoimmune thyroiditis (AIT) (146).

●        Increases the activity of selenoproteins that decrease reactive oxygen species (inflammation), increase natural killer activity, and increases glutathione (master antioxidant) levels (145,147).

●        Vital for lymphocyte (immune cell) proliferation (growth) and paramount in neutrophil (immune cell) destruction of bacteria (18).

●        Vital for activation of genetic signals that support immune function and vitality (18).

●        Glutamine is utilized by immune cells at high rates during catabolic conditions (post-surgery, sepsis, burns, and extreme exercise (18).

●        High in ECGC (epigallocatechin gallate) (26).

●        ECGC is shown to reduce body fat mass, increase fat oxidation(burning) and increase caloric expenditure during exercise (25).

●        Potent anti-inflammatory compound supporting glutathione production and inhibition of pro-inflammatory markers (cytokines) (26).

●        Reduces oxidative stress (chronic inflammation in the body) (26).

●        Serves as a methyl donor and as a precursor for the production of cell membranes (62).

●        Precursor for acetylcholine (neurotransmitter) which activates receptors in the central nervous system-mediated immune responses (α7nAchR) (64).

●        Lifelong choline supplementation may combat neurodegenerative diseases by reducing amyloid-β plaque load (plaques of degrading neurons) (62).

●        Reduces the concentration of total homocysteine (inflammation marker) in individuals with low levels of folate and other B vitamins (B₂, B₆, and B₁₂) (62).

●       Combats metabolic syndrome via reduced levels of triglycerides, total- and LDL-cholesterol (221).

●       Supports antioxidant function via reduced levels of reactive oxygen species and inflammatory markers (interleukin 6) (222).

●        The precursor to dopamine and is vital for dopamine synthesis in the brain (60).

●        Supports cognitive function in individuals with high amounts of stress and anxiety (60,61).

●        Increases dopamine levels in highly stressed individuals (60).

●       Supports antioxidant function via modulation of antioxidant enzyme expression, protection against oxidative damage, and reduced reactive oxygen species (31).

●       Supports cardiovascular health via reduced atherosclerosis, inhibiting lipid peroxidation, and improved endothelial vascular function (31).

●       Supports Cardiovascular health via reduction of systolic BP, LDL, and inflammatory biomarkers (224).

●       Supports antioxidant function via anti-inflammatory polyphenols that protect against DNA damage initiated by free radicals (225).

●       Combats major inflammatory pathways via anti-inflammatory change involving inflammation pathway (NF-κB inhibition) (225).

●       Supports blood sugar regulation via improved insulin sensitivity and pancreatic β-cell (cells responsible for secreting insulin) secretory capacity (226).

●       Fish oil consumption of 6 grams per day has been shown to reduce inflammation, reduce muscle soreness, and reduced the perception of pain in exercising individuals (76).

●       Increases skeletal muscle hypertrophy than individuals consuming only whey protein post-exercise (76).

●       Supports cardiovascular health by decreasing atrial fibrillation, atherosclerosis (plaque buildup), thrombosis, blood pressure, and supporting blood lipid profiles (cholesterol panel) (73,74,75).

●       Lowers blood pressure via increased production nitric oxide production and induced endothelial relaxation (75).

●       Supports healthy information by decreasing c-reactive protein (inflammatory markers) in the body and increasing insulin sensitivity (75,76).

●       Supports cognitive health by increasing the concentration of omega 3 fatty acids in the cell membranes of the cerebral cortex and synaptic vesicles (76).

●       Reduces prevalence of short-term memory loss in ADHD patients improved prefrontal cortex (PFC) pyramidal cells function (228).

●       Increases dopamine and acetylcholine release via maintenance of acetylcholine supply (228).

●       Reduces cortisol levels in the frontal Brian regions during stressful activity (228,229).

●       Combats neurodegenerative disease via improvement of cognitive function, daily living activity, and global clinical assessment in participants with Alzheimer’s disease (230).